Tumor surgery in this area of brain is very dangerous and the patient is recommended to radiation therapy and needle biopsy. The patient was a young man with severe cancer, the surgeon used ultrasonic aspirator and navigation technique by Transanal microscopic surgery. During the surgery Dr. Guive Sharifi (neurosurgeon) drained the tumor completely. The patient did not find any neural defects, Thanks God. Pathology results showed low-grade astrocytoma tumor, that’s very promising. This surgery is one of the most complicated surgery.