{"id":971,"date":"2018-03-06T15:01:54","date_gmt":"2018-03-06T11:31:54","guid":{"rendered":"http:\/\/dr-sharifi.adibdemo.ir\/2018\/03\/06\/%d8%b9%d9%84%d8%a7%d8%a6%d9%85-%d8%a7%d8%b5%d9%84%db%8c-%d8%b3%d9%86%d8%af%d8%b1%d9%88%d9%85-%da%a9%d9%88%d8%b4%db%8c%d9%86%da%af-%da%86%db%8c%d8%b3%d8%aa%d8%9f\/"},"modified":"2018-03-18T12:43:28","modified_gmt":"2018-03-18T09:13:28","slug":"cushings-syndrome","status":"publish","type":"post","link":"https:\/\/gsharifi.com\/en\/cushings-syndrome\/","title":{"rendered":"Cushing\u2019s syndrome"},"content":{"rendered":"

Cushing\u2019s syndrome<\/h2>\n
\n

1- 1 What is Cushing\u2019s syndrome?
\nCushing\u2019s syndrome occurs due to abnormally high levels of the hormone cortisol. This can happen for a variety of reasons. The most common cause is overuse of corticosteroid medications.
\nYour doctor may recommend several different diagnostic tests and treatments. In most cases, medication can help you manage your cortisol levels.
\n1- 2 What are the causes of Cushing\u2019s syndrome?
\nYour adrenal glands produce cortisol. It helps with a number of your body\u2019s functions, including:
\n\u2022 regulating blood pressure and the cardiovascular system
\n\u2022 reducing the immune system\u2019s inflammatory response
\n\u2022 converting carbohydrates, fats, and proteins into energy
\n\u2022 balancing the effects of insulin
\n\u2022 responding to stress
\nYour body may produce high levels of cortisol for a variety of reasons, including:
\n\u2022 high stress levels, including stress related to an acute illness, surgery, injury, or pregnancy, especially in the final trimester
\n\u2022 athletic training
\n\u2022 malnutrition
\n\u2022 alcoholism
\n\u2022 depression, panic disorders, or high levels of emotional stress
\nThe most common cause of Cushing\u2019s syndrome is the use of corticosteroid medications, such as prednisone, in high doses for a long period. Doctors can prescribe these medications to prevent rejection of a transplanted organ. They also use them to treat inflammatory diseases, such as lupus and arthritis. High doses of injectable steroids for treatment of back pain can also cause this syndrome.
\nLower dose steroids in the form of inhalants, such as those used for asthma, or creams, such as those prescribed for eczema, usually aren\u2019t enough to cause Cushing\u2019s syndrome.
\nOther causes include:
\n\u2022 a pituitary gland tumor in which the pituitary gland releases too much adrenocorticotropic hormone, which is also known as Cushing\u2019s disease
\n\u2022 ectopic ACTH syndrome, which causes tumors that usually occur in the lung, pancreas, thyroid, or thymus gland
\n\u2022 an adrenal gland abnormality or tumor
\nFamilial Cushing\u2019s syndrome is another possible cause. Cushing\u2019s syndrome isn\u2019t typically inherited, but it\u2019s possible to have an inherited tendency to develop tumors of the endocrine glands.
\nWhat are the symptoms of Cushing\u2019s syndrome?
\nThe most common symptoms of this condition are:
\n\u2022 weight gain
\n\u2022 obesity
\n\u2022 fatty deposits, especially in the midsection, the face (causing a round, moon-shaped face) and between the shoulders and the upper back (causing a buffalo hump)
\n\u2022 purple stretch marks on the breasts, arms, abdomen, and thighs
\n\u2022 thinning skin that bruises easily
\n\u2022 skin injuries that are slow to heal
\n\u2022 acne
\n\u2022 fatigue
\n\u2022 muscle weakness
\n\u2022 glucose intolerance
\n\u2022 increased thirst
\n\u2022 increased urination
\n\u2022 bone loss
\n\u2022 high blood pressure
\n\u2022 a headache
\n\u2022 cognitive dysfunction
\n\u2022 anxiety
\n\u2022 irritability
\n\u2022 depression
\n\u2022 an increased incidence of infections
\nWomen may also notice extra facial and body hair, as well as absent or irregular menstruation.
\nMen may also have:
\n\u2022 erectile dysfunction
\n\u2022 a loss of sexual interest
\n\u2022 decreased fertility
\nChildren with this condition are generally obese and have a slower rate of growth.
\nIf you don\u2019t get treatment for it, Cushing\u2019s syndrome can lead to:
\n\u2022 bone loss
\n\u2022 bone fractures
\n\u2022 muscle loss and weakness
\n\u2022 high blood pressure
\n\u2022 type 2 diabetes
\n\u2022 infections
\n\u2022 enlargement of a pituitary tumor
\n\u2022 kidney stones
\nCushing\u2019s syndrome due to pituitary tumors can interfere with the production of other hormones.
\nReference:
\nhttp:\/\/www.healthline.com\/health\/cushing-syndrome#complications6<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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